Психиатрия и психореаниматология

По данным этой книги наиболее опасными по отношению ко всем другим НЛ (атипикам и типикам) в смысле QT являются рисполепт и зелдокс, и еще хлорпромазин (под вопросом)
Интересно, gggDMN об этом знает?

Цитата:

а капсул по 20 мг не бывает.

Ziprasidone is available as capsules of 20 mg (blue/white)

Там же:
"DRUG INTERACTIONS: Ziprasidone has a modest effect on the electrical activity of the heart which can be seen on the electrocardiogram (EKG) as a prolongation of the QT-interval. (See discussion below.) Other drugs which also affect the QT interval can add to the effects of ziprasidone and lead to serious disturbances in the rhythm of the heart. Due to the potential for such additive effects on the QT interval, ziprasidone should not be taken with thioridazine (Mellaril), quinidine (Quinidex), moxifloxacin (Avelox), pimozide (Orap), sotalol (Betapace), dofetilide (Tikosyn), and sparfloxacin (Zagam).

Other drugs besides ziprasidone which may affect the heart rhythm (QTc prolongation in the EKG) include dofetilide, pimozide, quinidine, sotalol, procainamide, and sparfloxacin among others. QTc prolongation can infrequently result in serious, rarely fatal, irregular heartbeats. Consult your doctor or pharmacist for details. Ask for instructions about whether you need to stop any other QTc-prolonging drugs you may be using in order to minimize the risk of this effect. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: anti-Parkinson drugs (e.g., pramipexole, ropinirole), azole antifungals (e.g., ketoconazole, itraconazole), certain blood pressure medications (e.g., beta-blockers such as metoprolol or propranolol, "water pills" or diuretics such as furosemide or hydrochlorothiazide, or alpha-blockers such as doxazosin or prazosin). Tell your doctor or pharmacist if you take drugs that cause drowsiness, including: anti-anxiety drugs (e.g., diazepam), antihistamines that cause drowsiness (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep (e.g., sedatives), muscle relaxants, narcotic pain relievers (e.g., codeine), other psychiatric medicines (e.g., phenothiazines such as chlorpromazine, or tricyclics such as amitriptyline), tranquilizers."

В этом очень подробном (40 страниц) источнике:

"May cause QTc prolongation associated with the occurrence of torsades de pointes and sudden unexplained death; avoid
concomitant use of other drugs known to prolong QTc interval
Patients with bradycardia, hypokalemia, and/or hypomagnesemia may be at a greater risk for torsades de pointes and/or sudden death"